Regenerative Biology is an online Open Access journal dedicated to the timely publication of novel research that makes a significant contribution to the discipline of regenerative biology. Regenerative Biology is a key component of a unified effort to promote research on regeneration and engineering regenerative systems, which will include symposia, online videos, research prizes and an online mechanism to foster collaborations. We are interested in articles that focus on the basic biological mechanisms that underlie regeneration in key model systems and in mammals. Work that explicates the trade-offs between regenerative capacity, tumor suppression, immunity, wound healing and aging are of special interest. Research that takes an interdisciplinary approach making use of systems, computational/virtual or synthetic biology to catalyse research on regeneration is encouraged. We publish insightful commentaries on relevant commercial, political, ethical, and social ramifications of regenerative biology. We also encourage the submission of papers that describe new methods or innovative approaches and have implemented a special publication category for brief, provocative reports.

Each paper will be provided with an introduction by a member of the editorial staff or colleague that provides context, especially relative to work in other model systems. A mechanism to inform authors of related work in other systems, potential collaborators, of newly published work is also available.


Areas of interest include, but are not limited to:

Regenerative Biology

Non stem cell based regeneration
Dedifferentiation, Transdifferentiation, Redifferentiation
Stem cell function in regeneration
Muscle regeneration (satellite cells)
Cellular reprogramming
Regeneration models (planaria, hydra, urochordates (Botryllinae), salamanders, frogs (Xenopus), zebrafish,  mice ..etc)
Regeneration pathways
Computational analysis and simulation of regeneration
Stem cell niche
Somatic cell nuclear transfer
Bioinformatics and Systems biology

Synthetic Biology
Synthetic circuits (self-renewal, enhanced regenerative capacity)

Engineering tissue function
Engineering tissue organization
Engineering cellular plasticity

Content Types

All research format publications are subject to blind peer reviews, include the received/accepted dates, and follow the standard Regenerative Biology structure: abstract, introduction, methods, results, discussion, references, and supplementary materials and data. All sections, except the introduction are subdivided with headings that denote the research technique or discussion topic. We believe that confining authors to strict word limitations, while practical, forces authors to eliminate critical commentary in lieu of data inclusion. Abstracts are displayed in public archives and databases such as PubMed, and thus, the most widely read part of an article. Knowing this, we give authors more freedom to write the most important part of the paper.

An article is a full scientific report detailing important novel research. There are 6-8 main figures/tables in the article, with additional ones included in the supplementary materials and data section. The main text is 3,000 words (introduction, results, and discussion). The abstract is to be no more than 500 words, unreferenced. References are to number less than 50.

Brief Report
A brief report is a less substantial research article. There are 2-4 main figures/tables. The main text is no more than 2,000 words with a preceding 400 word abstract. References are to number less than 30.

Preliminary Report
A preliminary report is a brief report which contains 1 figure, 600 words, and less than 10 references. There is no abstract or methods section as the purpose of a preliminary report is to describe a work in progress to the scientific community. While not containing enough material for a brief report, it presents preliminary data supporting an important research finding. Preliminary reports can later be published as a full research article or a brief report which will be linked to the original preliminary report.

Correspondence is our most open format and includes any topic that would appeal to our readership, from scientific meetings, debates, opinions, to a summary of data. Discussion of research material is allowed, but only a in a general overview. The length of a correspondence can range from 1-4 pages, include up to 4 figures/tables, and 20 references.  The abstract is no more than 300 words.

News and views
News and views is to highlight significant breakthroughs published in other journals or to summarize important scientific trends.  News and views are usually less than 1/2 page.

A review is a scientific analysis and overview of the most current scientific literature on a specific topic. The author presents a concise summary while providing important insight to the compiled data as a whole, something that the authors may not have noted in the original works. Reviews can be up to 15 pages (not including references), include 10 figures/tables, and up to 100 references.  The abstract is no more than 500 words.

Commentary is a very open format but focuses on the commercial, ethical, legal, societal, or political issues of a topic, rather than the science. The commentary should give readers a unique perspective, new ideas, or different approach to a topic of interest. The style of a commentary is more open, and can be written for a more general audience.  Commentaries are usually 1-4 pages. The abstract is no more than 300 words.

A perspective is a scientific discussion of the primary literature but more focused than a review article. In this format, the author may propose new hypotheses, or contend current paradigms, with data from the literature. Perspectives are usually 1-4 pages, include up to 3 figures, and have up to 30 references. The abstract is no more than 300 words.

An open ended piece, where authors may discuss the scientific, commercial, ethical, legal, societal, or political future directions of regenerative biology. Editorial staff members contribute prescience pieces on publications that significantly advance the field. Prescience features are usually up to 2 pages and may include 2 figures, and 15 references. The abstract is no more than 200 words.

Media Types

Have you ever desired to explain the forethought or eureka moments that lead to your important work? Perhaps, you simply want to tell the world that you, like a gestalt, are more than the sum of your publications? Scientists include those who are eclectic, talented stylists, even passionate eccentrics, but our individualism is mostly absent from modern scientific publications.  The inclusion of Bioprints – brief videos or podcasts that accompany a published work provide a platform for self-expression and creativity.  Bioprints present an opportunity to reveal facets of authors that otherwise would only be apparent in personal interaction. Authors can inject personality into the presentation of their work, while readers learn about the people behind the text, the scope of their research, or perhaps even their scientific vision. Authors may also choose to include a podcast for readers to download or stream. Bioprints are not peer reviewed or edited by editorial staff. However, editors will review Bioprints  to ensure that they meet standards for publication. We encourage authors to edit their videos to meet file requirements.

  • Requirements for bioprint videos – 1080p resolution, 10MB max file size
  • Requirements for bioprint podcasts – 64kbps bit rate, 44,100 Khz sampling rate, mp3 format, 10MB max file size

Regenerative Biology will host an annual international conference to advance the field. Researchers will have an opportunity to share data, promote their work and establish new collaborations. Brainstorming sessions will be featured.



RB funding mechanism

Regenerative Biology (eISSN: 1553-6157) is published by Bio 2.0, a non-profit organization that is sponsored by Regenerative Sciences Institute, a 501(c)(3) non-profit.

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